Prognosis of patients treated for Cushing syndrome.

نویسندگان

  • Anna Aulinas
  • Elena Valassi
  • Susan M Webb
چکیده

Cushing syndrome (CS), due to an ACTH-secreting pituitary adenoma, adrenal tumors, or ectopic ACTH secretion, causes hypercortisolism. CS is associated with major morbidity, especially metabolic and cardiovascular complications, osteoporosis, psychiatric changes, and cognitive impairment. Despite biochemical "cure" of hypercortisolism and clinical improvement after effective treatment, these complications are only partially reversible. Exacerbation of prior autoimmune diseases is also seen. All of these lead to quality of life impairment and increased mortality. This review addresses the main comorbidities and long-term consequences of CS despite clinical and biochemical "cure".

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عنوان ژورنال:
  • Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion

دوره 61 1  شماره 

صفحات  -

تاریخ انتشار 2014